L Methylfolate

Product Description

L-Methylfolate, or 5-methyltetrahydrofolate, is a biologically active form of vitamin B9, essential for numerous cellular processes. Chemically, it is a water-soluble compound with the molecular formula C19H24N8O6. It exists as a chiral molecule, with the L-isomer being the biologically relevant form. L-Methylfolate is a yellow to orange-yellow crystalline powder, typically odorless and highly hygroscopic, readily absorbing moisture from the atmosphere. Its texture is fine and crystalline.As a methyl donor, L-Methylfolate plays a pivotal role in DNA synthesis, amino acid metabolism, and homocysteine remethylation. Unlike folic acid, its synthetic counterpart, L-Methylfolate bypasses the conversion steps required for cellular utilization, offering superior bioavailability.

USP of L Methylfolate:-

• Direct Utilization: No conversion required.
• Improved Absorption: Higher bioavailability.
• Targeted Delivery: Specific receptors for enhanced efficacy.
• Reduced Interactions: Fewer side effects.
• Suitable for Specific Populations: Beneficial for MTHFR gene mutations and neurological health.

Application of L Methylfolate:-

• Adjunctive Treatment in Major Depressive Disorder (MDD)
• Enhanced Antidepressant Efficacy: Augments the action of traditional antidepressants, potentially improving treatment outcomes May accelerate onset of antidepressant effects
• Neurotransmitter Synthesis Support: Facilitates the production of serotonin, dopamine, and norepinephrine Addresses potential folate-related factors in depression pathophysiolog
• Comprehensive Folate Deficiency Management
• Targeted Supplementation: Addresses folate deficiency more effectively than folic acid in certain populations Bypasses metabolic steps required for folic acid activation
• Genetic Considerations: Particularly beneficial for individuals with MTHFR gene mutations

 

FAQs of L-Methylfolate

Q: Can L-Methylfolate be taken with antidepressants?

A: Yes, L-Methylfolate is sometimes given together with antidepressants to aid with mood health. Although, it might help, ensure you inform your doctor before using supplements with your prescriptions.

Q: Is L-Methylfolate safe during pregnancy?

A: The use of L-Methylfolate is well tolerated and regarded as advantageous during pregnancy because it helps the development of fetal organs, mostly the brain. Nevertheless, always take it when it is prescribed and supervised by a doctor.

Q: Does L-Methylfolate have any side effects?

A: L-Methylfolate works well for the majority, although a few people may get mild effects such as nausea, headaches or irritability. Do not continue using it and speak to a doctor if you continue to experience or worsening symptoms.

Q: How should L-Methylfolate be stored?

A: Keep the L-Methylfolate bottle in a place that is cool, dry and shielded from sunlight and moisture. Always seal the front lid and store your chemicals where children cannot access them for safety.

Q: Can L-Methylfolate be taken daily?

A: Patients are usually instructed to take L-Methylfolate each day, though the right dosage is unique to every person. Take care of your medicine as your healthcare provider instructs so that it is effective long-term.